Prophylactic hydrocortisone in extremely preterm infants and brain MRI abnormality
نویسندگان
چکیده
منابع مشابه
Chorioamnionitis and outcome in extremely preterm infants.
INTRODUCTION Chorioamnionitis is a risk factor for preterm delivery. Intrauterine infection leads to the fetal inflammatory response which is characterised by elevated cytokine levels. Chorioamnionitis is reported to cause accelerated but abnormal lung maturation, resulting in decreased incidence of respiratory distress syndrome (RDS) but increased chronic lung disease (CLD), and predisposes th...
متن کاملNeurodevelopmental Outcomes of Extremely Preterm Infants Randomized to Stress Dose Hydrocortisone
OBJECTIVE To compare the effects of stress dose hydrocortisone therapy with placebo on survival without neurodevelopmental impairments in high-risk preterm infants. STUDY DESIGN We recruited 64 extremely low birth weight (birth weight ≤1000 g) infants between the ages of 10 and 21 postnatal days who were ventilator-dependent and at high-risk for bronchopulmonary dysplasia. Infants were random...
متن کاملOutcome trajectories in extremely preterm infants.
OBJECTIVE Methods are required to predict prognosis with changes in clinical course. Death or neurodevelopmental impairment in extremely premature neonates can be predicted at birth/admission to the ICU by considering gender, antenatal steroids, multiple birth, birth weight, and gestational age. Predictions may be improved by using additional information available later during the clinical cour...
متن کاملHydrocortisone treatment for bronchopulmonary dysplasia and brain volumes in preterm infants.
OBJECTIVE To assess whether there was an adverse effect on brain growth after hydrocortisone (HC) treatment for bronchopulmonary dysplasia (BPD) in a large cohort of infants without dexamethasone exposure. STUDY DESIGN Infants who received HC for BPD between 2005 and 2011 and underwent magnetic resonance imaging at term-equivalent age were included. Control infants born in Geneva (2005-2006) ...
متن کاملCranial ultrasound and MRI at term age in extremely preterm infants.
OBJECTIVES Conventional MRI at term age has been reported to be superior to cranial ultrasound (cUS) in detecting white matter (WM) abnormalities and predicting outcome in preterm infants. However, in a previous study cUS was performed during the first 6 weeks only and not in parallel to MRI at term age. Therefore, the aim of the present work was to study brain injuries in preterm infants perfo...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition
سال: 2020
ISSN: 1359-2998,1468-2052
DOI: 10.1136/archdischild-2019-317720